In Chicago's Humboldt Park neighborhood, the Vida/Sida Cacica Pageant brings together members of the Puerto Rican community to celebrate its transgender participants. The film follows Bianca, Julissa and Jolizza as they prepare for the pageant under the guidance of Ginger Valdez, an experienced transgender from the neighborhood. These trans women share stories of their transition, their family's varying reactions, and how they find support from within the community.