Scientist Jo Harding and her crack team of tornado chasers are pursuing the most destructive weatherfront to sweep through mid-America's Tornado Alley in 50 years. TV weatherman Bill Harding is trying to get his tornado-hunter wife, Jo, to sign divorce papers so he can marry his girlfriend Melissa. But Mother Nature, in the form of a series of intense storms has other plans. Jo's team is planning to launch revolutionary electronic sensors into the funnel of the tornado. They hope to obtain data to create an improved weather warning system. In order to get the sensors to work, the team must intercept the twister.