Harvard, America's most prestigious university and home to the world's greatest minds, is a place where some trailer park families - like John's (Jason Lee) - could never afford to go. But now, John's niece has the chance of a lifetime, and all she needs is the tuition that he had promised to pay if she got into a good college...$29,879...which he doesn't have. When John turns to his clueless friend Duff (Tom Green) for help, they wind up doing all the wrong things for all the right reasons.