Title:
The code breaker : Jennifer Doudna, gene editing, and the future of the human race
Author:
Edition:
First Simon & Schuster hardcover edition.
Publication Date:
2021
Publication Information:
New York : Simon & Schuster, 2021.
Physical Description:
xix, 536 pages : illustrations (chiefly color) ; 25 cm
ISBN:
9781982115852
Abstract:
Driven by a passion to understand how nature works and to turn discoveries into inventions, Doudna and her collaborators turned a curiosity of nature into an invention that will transform the human race: an easy-to-use tool that can edit DNA. Known as CRISPR, it opened a brave new world of medical miracles and moral questions. Isaacson explores the development of CRISPR and the race to create vaccines for coronavirus will hasten our transition to the next great innovation revolution. -- adapted from jacket
Contents:
Introduction. Into the breach -- Part one. The origins of life. Hilo ; The gene ; DNA ; The education of a biochemist ; The human genome ; RNA ; Twists and folds ; Berkeley -- Part two. CRISPR. Clustered repeats ; The Free Speech Movement Café ; Jumping in ; The yogurt makers ; Genentech ; The lab ; Caribou ; Emmanuelle Charpentier ; CRISPR-Cas9 ; Science, 2012 ; Dueling presentations -- Part three. Gene editing. A human tool ; The race ; Feng Zhang ; George Church ; Zhang tackles CRISPR ; Doudna joins the race ; Photo finish ; Doudna's final sprint ; Forming companies ; Mon amie ; The heroes of CRISPR ; Patents -- Part four. CRISPR in action. Therapies ; Biohacking ; DARPA and anti-CRISPR -- Part five. Public scientist. Rules of the road ; Doudna steps in -- Part six. CRISPR babies. He Jiankui ; The Hong Kong summit ; Acceptance -- Part seven. Moral questions. Red lines ; Thought experiments ; Who should decide? ; Doudna's ethical journey -- Part eight. Dispatches from the front. Quebec ; I learn to edit ; Watson revisited ; Doudna pays a visit -- Part nine. Coronavirus. Call to arms ; Testing ; The Berkeley lab ; Mammoth and Sherlock ; Coronavirus tests ; Vaccines ; CRISPR cures ; Cold Spring Harbor virtual ; The Nobel Prize.
Personal Subject:
Language:
English
