Life in Squares dramatizes the lives of the Bloomsbury Group, an influential set of artists and intellectuals. Told over 40 years, from the death of Queen Victoria to the Second World War, the story centers on the relationship between sisters Vanessa Bell and Virginia Woolf. As the narrative shifts between the decades, their lives intertwine; by the 1930s, Vanessa has settled into marriage and motherhood, and Virginia is enjoying huge public acclaim. Can the sisters truly escape the pall cast by their repressive parents, or will they ultimately inflict the same mistakes on generations to come?