A touching portrait of family and friendship, EZRA follows Max Bernal (Bobby Cannavale), a stand-up comedian living with his father (Robert De Niro), while struggling to co-parent his autistic son Ezra (introducing William Fitzgerald) with his ex-wife (Rose Byrne). When forced to confront difficult decisions about their son's future, Max and Ezra embark on a cross-country road trip that has a transcendent impact on both their lives.