Beginning with a single dealer who lands in a small Virginia town and sets about turning high school football stars into heroin overdose statistics, journalist Beth Macy endeavors to answer a grieving mother's question -- why her only son died -- and comes away with a harrowing story of greed and need. From the introduction of OxyContin in 1996, Macy parses how America embraced a medical culture where overtreatment with painkillers became the norm. The unemployed use painkillers both to numb the pain of joblessness and pay their bills, while privileged teens trade pills in cul-de-sacs, and even high school standouts fall prey to prostitution, jail, and death. Through human portraits of the families and first responders struggling to ameliorate this epidemic, each facet of the crisis comes into focus.